Aristea S Galanopoulou Selected Research

Infantile Spasms (West Syndrome)

1/2021	Antiepileptogenic effects of rapamycin in a model of infantile spasms due to structural lesions.
12/2018	Acquired parvalbumin-selective interneuronopathy in the multiple-hit model of infantile spasms: A putative basis for the partial responsiveness to vigabatrin analogs?
7/2017	Preclinical Screening for Treatments for Infantile Spasms in the Multiple Hit Rat Model of Infantile Spasms: An Update.
1/2017	Neuroinflammation in epileptogenesis: Insights and translational perspectives from new models of epilepsy.
12/2015	Neonatal and Infantile Epilepsy: Acquired and Genetic Models.
7/2015	Pathogenesis and new candidate treatments for infantile spasms and early life epileptic encephalopathies: A view from preclinical studies.
4/2014	Mechanisms of epileptogenesis in pediatric epileptic syndromes: Rasmussen encephalitis, infantile spasms, and febrile infection-related epilepsy syndrome (FIRES).
1/2014	Efficacy and tolerability of the galanin analog NAX 5055 in the multiple-hit rat model of symptomatic infantile spasms.
1/2014	CPP-115, a vigabatrin analogue, decreases spasms in the multiple-hit rat model of infantile spasms.
9/2013	Basic mechanisms of catastrophic epilepsy -- overview from animal models.

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Aristea S Galanopoulou Research Topics

Disease

21	Seizures (Absence Seizure) 01/2021 - 12/2002
18	Epilepsy (Aura) 01/2021 - 01/2007
14	Infantile Spasms (West Syndrome) 01/2021 - 07/2010
12	Spasm (Spasms) 01/2021 - 03/2010
6	Status Epilepticus (Complex Partial Status Epilepticus) 02/2015 - 05/2003
2	Inflammation (Inflammations) 01/2021 - 01/2017
2	Temporal Lobe Epilepsy 06/2018 - 07/2012
2	Rett Syndrome (Rett's Disorder) 01/2016 - 01/2016
2	Myoclonic Epilepsies (Myoclonic Encephalopathy) 12/2015 - 07/2015
2	Down Syndrome (Down's Syndrome) 07/2015 - 09/2013
2	Epileptic Syndromes 04/2014 - 07/2012
2	Tuberous Sclerosis (Bourneville's Disease) 07/2012 - 08/2011
1	Stroke (Strokes) 01/2021
1	Hemorrhage 01/2019
1	Vitamin B 6 Deficiency (Pyridoxine Deficiency) 06/2018
1	Autism Spectrum Disorder 01/2016
1	Brain Diseases (Brain Disorder) 12/2015
1	Fever (Fevers) 04/2014
1	Neuroinflammatory Diseases 04/2014
1	Infections 04/2014
1	Multiple Hamartoma Syndrome (Cowden's Disease) 07/2012
1	Polyhydramnios 07/2012
1	Neurofibromatosis 1 (Neurofibromatosis Type I) 07/2012
1	Inborn Genetic Diseases (Disease, Hereditary) 07/2012
1	Malformations of Cortical Development 07/2012
1	Megalencephaly 07/2012
1	Disease Progression 10/2011
1	Cognitive Dysfunction 08/2011
1	Ischemia 01/2007
1	Wounds and Injuries (Trauma) 01/2007

Drug/Important Bio-Agent (IBA)

6	Pharmaceutical PreparationsIBA 01/2017 - 09/2011
6	GABA-A Receptors (GABA(A) Receptor)IBA 01/2011 - 10/2003
4	Vigabatrin FDA Link 12/2018 - 03/2010
4	Kainic Acid (Kainate)IBA 06/2018 - 05/2003
4	Adrenocorticotropic Hormone (ACTH)FDA Link 04/2014 - 03/2010
4	gamma-Aminobutyric Acid (GABA)IBA 01/2011 - 01/2004
3	Sirolimus (Rapamycin)FDA Link 01/2021 - 08/2011
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 01/2017
2	LipopolysaccharidesIBA 01/2021 - 01/2017
2	Biomarkers (Surrogate Marker)IBA 01/2017 - 10/2011
2	CytokinesIBA 01/2017 - 01/2017
2	Betamethasone (Celestone)FDA Link 07/2015 - 09/2013
2	N-Methylaspartate (NMDA)IBA 07/2015 - 09/2013
2	Tetrodotoxin (Tetradotoxin)IBA 07/2015 - 09/2013
2	Anticonvulsants (Antiepileptic Drugs)IBA 02/2015 - 01/2011
2	Flurothyl (Flurotyl)IBA 02/2015 - 12/2002
2	ChloridesIBA 01/2011 - 01/2007
2	MuscimolIBA 01/2004 - 10/2003
1	Hypnotics and Sedatives (Sedatives)IBA 06/2020
1	Calcium Channels (Calcium Channel)IBA 01/2019
1	IronIBA 01/2019
1	ParvalbuminsIBA 12/2018
1	Amino Acids FDA Link 06/2018
1	Glucose (Dextrose)FDA LinkGeneric 06/2018
1	Fatty Acids (Saturated Fatty Acids)IBA 06/2018
1	MetalsIBA 06/2018
1	GoldIBA 12/2016
1	AnionsIBA 01/2016
1	Glatiramer Acetate (Copaxone)FDA Link 01/2016
1	TOR Serine-Threonine KinasesIBA 12/2015
1	Lidocaine (Xylocaine)FDA LinkGeneric 11/2015
1	LithiumIBA 02/2015
1	Pilocarpine (Ocusert)FDA LinkGeneric 02/2015
1	Phenobarbital (Luminal)FDA Link 02/2015
1	Biological FactorsIBA 12/2014
1	BenzodiazepinesIBA 10/2014
1	SteroidsIBA 04/2014
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2014
1	4-Aminobutyrate Transaminase (4 Aminobutyrate Transaminase)IBA 01/2014
1	(1S,3S)- 3- amino- 4- difluoromethylenecyclopentanecarboxylic acidIBA 01/2014
1	GalaninIBA 01/2014
1	NAX 5055IBA 01/2014
1	Type 1 Galanin ReceptorIBA 01/2014
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2014
1	Corticotropin-Releasing HormoneIBA 09/2013
1	AMPA Receptors (AMPA Receptor)IBA 09/2012
1	Phosphotransferases (Kinase)IBA 07/2012
1	trans-sodium crocetinate (crocetin)IBA 07/2012
1	TensinsIBA 07/2012
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 07/2012
1	Neurofibromin 1 (Neurofibromin)IBA 07/2012
1	Sodium Channels (Sodium Channel)IBA 09/2011
1	Phenytoin (Dilantin)FDA LinkGeneric 09/2011
1	S-2-O-carbamoyl-1-o-chlorophenyl-ethanolIBA 09/2011
1	Mechanistic Target of Rapamycin Complex 1IBA 08/2011
1	Ribosomal Proteins (Ribosomal Protein)IBA 08/2011
1	Bumetanide (Bumex)FDA LinkGeneric 01/2011
1	Messenger RNA (mRNA)IBA 01/2007
1	CationsIBA 01/2007
1	K Cl- CotransportersIBA 01/2007
1	Testosterone (Sustanon)FDA Link 01/2004
1	Estrogens (Estrogen)FDA Link 05/2003
1	Gonadal Steroid Hormones (Sex Hormones)IBA 12/2002

Therapy/Procedure

17	Therapeutics 01/2021 - 07/2010
1	Injections 01/2017
1	Electrodes (Electrode) 11/2015
1	Intraperitoneal Injections 09/2011
1	Castration 01/2004